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PubMed · 16955974

Studies on autoprothrombin C thrombin relationship.

R H Landaburu·O Abdala·S Fulginiti·J Curtino
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Abstract

In every prothrombin activation two different enzymatic reactions can be distinguished. The first reaction is the prothrombin disappearance and the second one is the thrombin formation. Autoprothrombin C catalyzes both reactions and thrombin only the first one. The inhibition of thrombin with heparin allows a more complete activation of the thrombin. The two reactions can be independently catalyzed by different substances. Heparin by itself can provide the environment for activation.

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AnimalsCattleEnzyme ActivationFactor XaHeparinKineticsThrombinJournal ArticleResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't

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R H Landaburu, O Abdala, S Fulginiti, J Curtino. 1965-09-01. Studies on autoprothrombin C thrombin relationship.. https://pubmed.ncbi.nlm.nih.gov/16955974/

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