Quantum dot encapsulation in viral capsids.

Suraj K Dixit; Nancy L Goicochea; Marie-Christine Daniel; Ayaluru Murali; Lyudmila Bronstein; Mrinmoy De; Barry Stein; Vincent M Rotello; C Cheng Kao; Bogdan Dragnea

doi:10.1021/nl061165u

PubMed · 16968014

Quantum dot encapsulation in viral capsids.

Suraj K Dixit·Nancy L Goicochea·Marie-Christine Daniel·Ayaluru Murali·Lyudmila Bronstein·Mrinmoy De·Barry Stein·Vincent M Rotello·C Cheng Kao·Bogdan Dragnea

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Abstract

Incorporation of CdSe/ZnS semiconductor quantum dots (QDs) into viral particles provides a new paradigm for the design of intracellular microscopic probes and vectors. Several strategies for the incorporation of QDs into viral capsids were explored; those functionalized with poly(ethylene glycol) (PEG) can be self-assembled into viral particles with minimal release of photoreaction products and enhanced stability against prolonged irradiation.

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Capsid Coated Materials, Biocompatible Molecular Probe Techniques Nanotechnology Quantum Dots Virus Assembly Journal Article Research Support, N.I.H., Extramural Research Support, U.S. Gov't, Non-P.H.S.

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Suraj K Dixit, Nancy L Goicochea, Marie-Christine Daniel, Ayaluru Murali, Lyudmila Bronstein, Mrinmoy De, Barry Stein, Vincent M Rotello, C Cheng Kao, Bogdan Dragnea. 2006. Quantum dot encapsulation in viral capsids.. https://doi.org/10.1021/nl061165u

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