Genetic parts to program bacteria.

Christopher A Voigt

doi:10.1016/j.copbio.2006.09.001

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Genetic parts to program bacteria.

Christopher A Voigt

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Abstract

Genetic engineering is entering a new era, where microorganisms can be programmed using synthetic constructs of DNA encoding logic and operational commands. A toolbox of modular genetic parts is being developed, comprised of cell-based environmental sensors and genetic circuits. Systems have already been designed to be interconnected with each other and interfaced with the control of cellular processes. Engineering theory will provide a predictive framework to design operational multicomponent systems. On the basis of these developments, increasingly complex cellular machines are being constructed to build specialty chemicals, weave biomaterials, and to deliver therapeutics.

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Bacteria Bacterial Proteins Gene Expression Regulation Genetic Engineering Genome, Bacterial Models, Genetic Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.Review

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Christopher A Voigt. 2006-09-15. Genetic parts to program bacteria.. https://doi.org/10.1016/j.copbio.2006.09.001

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