Evolution of cytokeratin expression in developing human tooth germ.

A Pelissier; J P Ouhayoun; M H Sawaf; N Forest

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PubMed · 1698767

Evolution of cytokeratin expression in developing human tooth germ.

A Pelissier·J P Ouhayoun·M H Sawaf·N Forest

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Abstract

Cytokeratin expression by the developing human enamel organ between the 10th and the 23rd gestational week was studied by indirect immunofluorescence microscopy technique using a panel of 15 monoclonal antibodies. The results showed that five antibodies (RKSE 60, Kk 8-60, EE 21-6, 6B10 and 1 C-7) were never reactive, that five antibodies (RCK 102, 42.39.13.1, Ks 19 and Pan 1-8) were always positive and that five antibodies (KB 37, RPN 11-62, Ks 13.1, Ks 8-12 and Ks 18.174) obtained or increased their positivity between weeks 12 and 13. It was concluded that a switch in cytokeratin expression occurred around the 12th-13th weeks. No further important change could be noticed after this period. So it is suggested that final cell differentiation was initiated at weeks 12-13.

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Amelogenesis Antibodies, Monoclonal Dental Enamel Enamel Organ Fetus Fluorescent Antibody Technique Gestational Age Humans Keratins Odontogenesis Tooth Germ Journal Article

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A Pelissier, J P Ouhayoun, M H Sawaf, N Forest. 1990. Evolution of cytokeratin expression in developing human tooth germ.. https://pubmed.ncbi.nlm.nih.gov/1698767/

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