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PubMed · 16991036

[Ischemic pre- and postconditioning].

G Heusch·R Schulz
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Abstract

One or several short cycles of ischemia/reperfusion before (preconditioning) or after (postconditioning) a sustained coronary occlusion with subsequent reperfusion reduce the ultimate infarct size. The protection is potent, but limited to a narrow time frame. In animal experiments a complex signal transduction cascade was identified which results specifically in a reduction of reperfusion injury. There is evidence for both ischemic pre-and postconditioning in patients with coronary artery disease.

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AnimalsHumansIschemic Preconditioning, MyocardialMyocardial InfarctionMyocardial ReperfusionSignal TransductionEnglish AbstractJournal ArticleReview

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G Heusch, R Schulz. 2006-09-29. [Ischemic pre- and postconditioning].. https://doi.org/10.1055/s-2006-951349

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