SPINE high-throughput crystallization, crystal imaging and recognition techniques: current state, performance analysis, new technologies and future aspects.

Ian M Berry; O Dym; R M Esnouf; K Harlos; R Meged; A Perrakis; J L Sussman; T S Walter; J Wilson; Albrecht Messerschmidt

doi:10.1107/s090744490602943x

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PubMed · 17001091

SPINE high-throughput crystallization, crystal imaging and recognition techniques: current state, performance analysis, new technologies and future aspects.

Ian M Berry·O Dym·R M Esnouf·K Harlos·R Meged·A Perrakis·J L Sussman·T S Walter·J Wilson·Albrecht Messerschmidt

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Abstract

This paper reviews the developments in high-throughput and nanolitre-scale protein crystallography technologies within the remit of workpackage 4 of the Structural Proteomics In Europe (SPINE) project since the project's inception in October 2002. By surveying the uptake, use and experience of new technologies by SPINE partners across Europe, a picture emerges of highly successful adoption of novel working methods revolutionizing this area of structural biology. Finally, a forward view is taken of how crystallization methodologies may develop in the future.

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Crystallography Image Processing, Computer-Assisted Nanotechnology Plastics Proteins Proteomics Quality Control Robotics Journal Article Research Support, Non-U.S. Gov't Review

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Ian M Berry, O Dym, R M Esnouf, K Harlos, R Meged, A Perrakis, J L Sussman, T S Walter, J Wilson, Albrecht Messerschmidt. 2006-09-19. SPINE high-throughput crystallization, crystal imaging and recognition techniques: current state, performance analysis, new technologies and future aspects.. https://doi.org/10.1107/s090744490602943x

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