Dendritic protein synthesis, synaptic plasticity, and memory.

Michael A Sutton; Erin M Schuman

doi:10.1016/j.cell.2006.09.014

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Dendritic protein synthesis, synaptic plasticity, and memory.

Michael A Sutton·Erin M Schuman

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Abstract

Considerable evidence suggests that the formation of long-term memories requires a critical period of new protein synthesis. Recently, the notion that some of these newly synthesized proteins originate through local translation in neuronal dendrites has gained some traction. Here, we review the experimental support for this idea and highlight some of the key questions outstanding in this area.

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Animals Dendrites Learning Memory Neuronal Plasticity Protein Biosynthesis Proteome RNA, Messenger Synapses Time Factors Journal Article Review

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Michael A Sutton, Erin M Schuman. 2006-10-06. Dendritic protein synthesis, synaptic plasticity, and memory.. https://doi.org/10.1016/j.cell.2006.09.014

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