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Production system for biodegradable polyester polyhydroxybutyrate by Corynebacterium glutamicum.

Sung-Jin Jo·Michihisa Maeda·Toshihiko Ooi·Seiichi Taguchi
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Abstract

A biosynthetic pathway for poly(3-hydroxybutyrate) [P(3HB)] production by Corynebacterium glutamicum was developed by introducing the phbCAB operon derived from Ralstonia eutropha. P(3HB) synthase activity was detected in this recombinant C. glutamicum carrying a cell surface protein gene promoter. Intracellular P(3HB) was microscopically observed as inclusion granules and its content was calculated to be 22.5% (w/w) with a number average molecular weight of 2.1x10(5) and a polydispersity of 1.63.

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Corynebacterium glutamicumCupriavidus necatorHydroxybutyratesInclusion BodiesOperonPolyestersPolyhydroxybutyratesJournal ArticleResearch Support, Non-U.S. Gov't

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Sung-Jin Jo, Michihisa Maeda, Toshihiko Ooi, Seiichi Taguchi. 2006. Production system for biodegradable polyester polyhydroxybutyrate by Corynebacterium glutamicum.. https://doi.org/10.1263/jbb.102.233

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