PubMed · 17057424
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Ann F Vansant. 2003. Are we better off?. https://doi.org/10.1097/01.pep.0000057395.30633.78
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Precision oncology relies on integrating tumour fraction, variant allele frequency, clonal haematopoiesis of indeterminate potential assessment, pathogenicity, and clinical context into next-generation sequencing interpretation, enabling biologically informed and clinically meaningful treatment decisions while reducing the risk of overinterpreting nontumour or nonactionable genomic alterations.