BMP4 expression in the developing rat retina.

Yuka Maruyama; Sumiko Mikawa; Yoshihiro Hotta; Kohji Sato

doi:10.1016/j.brainres.2006.08.130

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BMP4 expression in the developing rat retina.

Yuka Maruyama·Sumiko Mikawa·Yoshihiro Hotta·Kohji Sato

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Abstract

We investigated the expression of bone morphogenetic protein-4 (BMP4) in the developing retina. At E19, we found very intense BMP4 immunoreactivity (IR) in the nerve fiber layer. At P1, the inner plexiform layer exhibited very strong BMP4-IR. Thereafter, abundant BMP4 expression was kept to the adult period. These results suggest that BMP4 plays pivotal roles in the retina not only in the early embryonic period but also in the late embryonic and postnatal periods, and even in the adult.

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Animals Bone Morphogenetic Protein 4 Bone Morphogenetic Proteins Gene Expression Regulation, Developmental Male Nerve Fibers Rats Rats, Wistar Retina Tissue Distribution Journal Article Research Support, Non-U.S. Gov't

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Yuka Maruyama, Sumiko Mikawa, Yoshihiro Hotta, Kohji Sato. 2006-10-27. BMP4 expression in the developing rat retina.. https://doi.org/10.1016/j.brainres.2006.08.130

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