Stabilized porous phospholipid nanoshells.

Zhiliang Cheng; Gemma D D'Ambruoso; Craig A Aspinwall

doi:10.1021/la061542i

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PubMed · 17073472

Stabilized porous phospholipid nanoshells.

Zhiliang Cheng·Gemma D D'Ambruoso·Craig A Aspinwall

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Abstract

Chemically stabilized, porous phospholipid nanoshells (PPNs) were prepared via copolymerization of reactive monomers with unilamellar bis-Sorbyl phosphatidylcholine vesicles. The resulting PPN vesicular assemblies possess a highly porous membrane structure that allows passage of small molecules, which can react with encapsulated proteins and reporters. The unique combination of membrane stability and porosity will prove useful for preparing nanometer-sized sensor, container, and reactor platforms stable in harsh chemical and biological environments.

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Genes, Reporter HeLa Cells Humans Microscopy, Electron, Transmission Molecular Structure Nanostructures Phospholipids Porosity Journal Article Research Support, N.I.H., Extramural

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Zhiliang Cheng, Gemma D D'Ambruoso, Craig A Aspinwall. 2006-11-07. Stabilized porous phospholipid nanoshells.. https://doi.org/10.1021/la061542i

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