Omalizumab for severe asthma?

PubMed · 17089921

Omalizumab for severe asthma?

Abstract

Up to 5% of patients with asthma have severe disease (i.e., around 250,000 people in the U.K.). This means their asthma remains uncontrolled despite optimal treatment with high-dose inhaled corticosteroid plus additional therapy or a regularoral corticosteroid, and with no otherexplanations such as poor adherenceto therapy and otherdiagnoses such as vocal cord dysfunction. Omalizumab (pronounced oh-ma-liz-oo-mab) (Xolair-Novartis) is a monoclonal antibody to IgE that is available in the U.K. as add-on therapy for people aged 12 years and over with severe persistent asthma that has an important allergic component. What benefits, if any, does omalizumab offer to such patients?

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Anti-Asthmatic Agents Antibodies, Anti-Idiotypic Antibodies, Monoclonal Antibodies, Monoclonal, Humanized Asthma Clinical Trials as Topic Humans Omalizumab Journal Article Review

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2006. Omalizumab for severe asthma?. https://pubmed.ncbi.nlm.nih.gov/17089921/

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