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Relating two techniques for handling uncertainties in IMRT optimization.

J Unkelbach·U Oelfke
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Abstract

Radiotherapy treatment planning is associated with uncertainties. Examples are uncertainties in the tumour location due to organ movement or the inter/intra observer variability in target definition. Different approaches to incorporate uncertainties into IMRT optimization have been proposed. In this note, we point out a relation between two previously published methods: the coverage probability approach and the concept of optimizing the expectation value of an objective function that depends on a set of random variables. Both concepts are generally different, but turn out to be equivalent in special cases.

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Biophysical PhenomenaBiophysicsHumansNeoplasmsProbabilityRadiotherapy, Intensity-ModulatedUncertaintyComparative StudyJournal Article

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J Unkelbach, U Oelfke. 2006-11-08. Relating two techniques for handling uncertainties in IMRT optimization.. https://doi.org/10.1088/0031-9155%2F51%2F23%2Fn04

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