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PubMed · 1711855

Antigen presentation: structural themes and functional variations.

T J Braciale·V L Braciale
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Abstract

T cells recognize nonnative processed fragments of antigens presented in association with major histocompatibility complex (MHC) class I or class II molecules. Recently, an accumulating body of evidence has provided a functional linkage between antigen presentation events and the cell biology of MHC molecule assembly and transport. In this review Thomas and Vivian Braciale synthesize these developments into a cohesive model of MHC assembly and antigen presentation pathways.

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AnimalsAntigen-Presenting CellsAntigensCytotoxicity, ImmunologicEndoplasmic ReticulumEpitopesGolgi ApparatusHistocompatibility Antigens Class IHistocompatibility Antigens Class IIHumansMiceModels, BiologicalPeptidesReceptors, Antigen, T-CellT-LymphocytesTumor Cells, CulturedJournal ArticleReview

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T J Braciale, V L Braciale. 1991. Antigen presentation: structural themes and functional variations.. https://doi.org/10.1016/0167-5699(91)90096-c

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