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PubMed · 17160

Transmitter release during repetitive stimulation: selective changes produced by Sr2+ and Ba2+.

J E Zengel·K L Magleby
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Abstract

The addition of Sr2+ or Ba2+ to the solution bathing the frog neuromuscular junction leads to an increased release of transmitter by each nerve impulse during and following repetitive stimulation. The mechanisms by which Sr2+ and Ba2+ increase release are not the same. Each ion appears to act selectively on a different process involved in transmitter release.

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AnimalsAnuraBariumCalciumElectric StimulationMagnesiumMembrane PotentialsMotor EndplateNeuromuscular JunctionNeurotransmitter AgentsRana pipiensStrontiumTime FactorsJournal ArticleResearch Support, U.S. Gov't, P.H.S.

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J E Zengel, K L Magleby. 1977-07-01. Transmitter release during repetitive stimulation: selective changes produced by Sr2+ and Ba2+.. https://doi.org/10.1126/science.17160

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