Statistical issues in clinical trial design.

Kenneth R Hess

doi:10.1007/bf02951426

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Statistical issues in clinical trial design.

Kenneth R Hess

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Abstract

This paper reviews some of the more salient recent developments in statistical aspects of clinical trial design methodology and suggests that more emphasis be placed on rigorous assessments of the new methodologies to place them in the context of existing methods, demonstrate their claimed advantages, and fully disclose their remaining limitations.

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Kenneth R Hess. 2007. Statistical issues in clinical trial design.. https://doi.org/10.1007/bf02951426

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