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Micro-reactors for PET tracer labeling.

S Y Lu·V W Pike
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Abstract

Miniaturization of PET radiosynthesis devices (micro-reactors or microfluidic systems) is an emerging area that has the potential to deliver many advantages, such as more efficient use of hot-cell space for production of multiple radiotracers; use of less non-radioactive precursor for saving precious material and a reduced separation challenge; highly controlled, reproducible and reliable radiotracer production; and cheap, interchangeable, disposable and quality-assured radiochemistry processors. Several 'proof of principle' examples along with basics of micro-reactor flow control, mixing principle and design, and device fabrication are discussed in this chapter.

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AnimalsCarbon RadioisotopesElectrochemistryFluorine RadioisotopesHumansKineticsPositron-Emission TomographyTrace ElementsJournal ArticleResearch Support, N.I.H., IntramuralReview

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S Y Lu, V W Pike. 2007. Micro-reactors for PET tracer labeling.. https://doi.org/10.1007/978-3-540-49527-7_10

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