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Mitoproteome: human heart mitochondrial protein sequence database.

Purnima Guda·Shankar Subramaniam·Chittibabu Guda
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Abstract

The human mitochondrial proteome database has been developed by deriving data from a combination of public repositories and experimental and computational prediction methods. The experimental data is derived from highly purified mitochondria from human heart tissue, whereas predictions have been performed by MITOPRED, a genome-scale method for the prediction of nucleus-encoded mitochondrial proteins. Mitochondrial protein sequences from different sources have been clustered to generate a nonredundant dataset. Annotations related to the protein function, structure, disease association, pathways, and so on are collected from a number of public databases using commonly used UNIX and Perl scripts. This chapter provides a detailed description of various data sources and methods used to download, curate, parse, and generate meaningful annotations from primary as well as derived databases.

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Computational BiologyDatabases, ProteinHumansMitochondria, HeartMitochondrial ProteinsProteomeJournal Article

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Purnima Guda, Shankar Subramaniam, Chittibabu Guda. 2007. Mitoproteome: human heart mitochondrial protein sequence database.. https://doi.org/10.1385/1-59745-214-9%3A375

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