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PubMed · 17172836

Regulation, cell differentiation and protein-based inheritance.

Fabienne Malagnac·Philippe Silar
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Abstract

Recent research using fungi as models provide new insight into the ability of regulatory networks to generate cellular states that are sufficiently stable to be faithfully transmitted to daughter cells, thereby generating epigenetic inheritance. Such protein-based inheritance is driven by infectious factors endowed with properties usually displayed by prions. We emphasize the contribution of regulatory networks to the emerging properties displayed by cells.

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Cell DifferentiationEpigenesis, GeneticFungal ProteinsGene Expression Regulation, FungalMAP Kinase Signaling SystemModels, BiologicalModels, GeneticPrionsSignal TransductionJournal ArticleResearch Support, Non-U.S. Gov'tReview

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Fabienne Malagnac, Philippe Silar. 2006-11-15. Regulation, cell differentiation and protein-based inheritance.. https://doi.org/10.4161/cc.5.22.3465

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