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PubMed · 1726583

Ionic channels: modulation by G proteins and by phosphorylation.

H Reuter·E Sigel
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Abstract

The gating of ion channels may be modulated by G proteins or by phosphorylation. Direct coupling between G proteins and ion channels has been shown in excised patches of membrane. Steps must now be taken to study the protein domains of G proteins and ion channels involved in the mutual interaction. The concept of channel modulation by protein kinases has recently been extended to include additional types of ion channel.

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AnimalsGTP-Binding ProteinsHumansIon ChannelsPhosphorylationJournal ArticleReview

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H Reuter, E Sigel. 1991. Ionic channels: modulation by G proteins and by phosphorylation.. https://doi.org/10.1016/0959-4388(91)90007-t

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