PubMed Health⌕ Search
Home/Archive/PubMed

PubMed · 1732923

Prebiopsy needle localization. Methods, problems, and expected results.

M J Homer·T J Smith·H Safaii
View original source ↗Export metadata ↓

Abstract

The use of mammography to screen patients for the presence of early breast cancer results in the detection of nonpalpable lesions. As screening becomes more widespread, the number of needle localizations performed will continue to increase. This procedure requires involvement of the radiologist, surgeon, and pathologist. Close cooperation between these disciplines will ensure optimal patient care.

Explore related subjects

BreastBreast NeoplasmsFemaleHumansMammographyNeedlesJournal ArticleReview

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

M J Homer, T J Smith, H Safaii. 1992. Prebiopsy needle localization. Methods, problems, and expected results.. https://pubmed.ncbi.nlm.nih.gov/1732923/

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

PubMed1992

Interaction of gangliosides with the methyltransferase-I of microsomes from normal and neoplastic human mammary gland.

The activity of the phospholipid methyltransferase-I, which catalyzes the rapid transmethylation of phosphatidylethanolamine to phosphatidylcholine, was found to be about 6-fold enhanced in microsomal membranes of breast cancer with respect to the level found in normal human mammary gland. Exogenous gangliosides GM1 and GM2 added to neoplastic breast microsomes induced progressive inhibition of the methyltransferase activity. In contrast, in microsomal membranes of non-neoplastic breast tissue treated with these gangliosides, the methyltransferase activity was markedly increased. The addition of cholesterol to these microsomes led to complete inhibition of the GM1-stimulated enzyme activity. The methyltransferase activity was not affected by GM3 alone in either type of tissue. Experiments carried out on non-neoplastic microsomes revealed that the phospholipid methyltransferase-I was affected by that portion of gangliosides which remained stable associated to microsomal membranes.

Breast↗