Copper resistance determinants in bacteria.

N L Brown; D A Rouch; B T Lee

doi:10.1016/0147-619x(92)90005-u

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PubMed · 1741459

Copper resistance determinants in bacteria.

N L Brown·D A Rouch·B T Lee

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Abstract

Copper is an essential trace element that is utilized in a number of oxygenases and electron transport proteins, but it is also a highly toxic heavy metal, against which all organisms must protect themselves. Known bacterial determinants of copper resistance are plasmid-encoded. The mechanisms which confer resistance must be integrated with the normal metabolism of copper. Different bacteria have adopted diverse strategies for copper resistance, and this review outlines what is known about bacterial copper resistance mechanisms and their genetic regulation.

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Amino Acid Sequence Bacteria Bacterial Proteins Copper Drug Resistance, Microbial Escherichia coli Genes, Bacterial Molecular Sequence Data Sequence Homology, Nucleic Acid Comparative Study Journal Article Research Support, Non-U.S. Gov't Review

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N L Brown, D A Rouch, B T Lee. 1992. Copper resistance determinants in bacteria.. https://doi.org/10.1016/0147-619x(92)90005-u

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