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Quality control in antimicrobial disk susceptibility testing: a Belgian multicenter study.

S Lauwers·J Philippe·A Van Zeebroeck·D Pierard·M P Derde·L Kaufman
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Abstract

A Belgian multicenter trial was conducted to evaluate problems encountered with quality control results of antimicrobial disk susceptibility testing and to compare the performance of BBL disks and Rosco tablets. Over a period of four weeks 18 laboratories daily tested three reference strains against eight antibiotics. A standardised method was used by all participants. For all results together 10.4% and 7.3% of the measurements with BBL disks and Rosco tablets, respectively, were outside the recommended range. Major problems were observed for some specific strain-antibiotic combinations. Standard deviations were similar for both systems; their precision was comparable. The results suggest that cooperation between manufacturers and some reference laboratories could be improved in order to establish optimal quality control limits.

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Anti-Bacterial AgentsBacteriaBelgiumEscherichia coliMicrobial Sensitivity TestsPseudomonas aeruginosaQuality ControlStaphylococcus aureusClinical TrialComparative StudyJournal ArticleMulticenter Study

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S Lauwers, J Philippe, A Van Zeebroeck, D Pierard, M P Derde, L Kaufman. 1991. Quality control in antimicrobial disk susceptibility testing: a Belgian multicenter study.. https://doi.org/10.1007/bf01975819

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