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PubMed · 1755971

T-cell tolerance to viruses.

R Ahmed
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Abstract

T-cell tolerance to self antigens is maintained by events that occur within the thymus and in the periphery. Mechanisms that operate on immature T cells within the thymus are effective in induction of tolerance to viruses, but mechanisms of tolerizing mature T cells are likely to break down. This failure of peripheral mechanisms to induce T-cell tolerance to viruses has implications for autoimmunity and for treatment of chronic viral infections.

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AnimalsAutoimmunityImmune ToleranceImmunity, CellularMiceT-LymphocytesVirus DiseasesJournal ArticleReview

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BibTeXRIS

R Ahmed. 1991. T-cell tolerance to viruses.. https://doi.org/10.1016/0952-7915(91)90006-m

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