From linked marker to gene.

C Wicking; B Williamson

doi:10.1016/0168-9525(91)90310-m

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From linked marker to gene.

C Wicking·B Williamson

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Abstract

An area of increasing importance in human genetics research is the strategy of 'reverse genetics' or 'positional cloning', whereby a gene associated with a genetic disease is isolated on the basis of its approximate chromosomal position. This article and the accompanying centrepage diagram describe the main features of this strategy and outline the techniques involved; they are designed to be used for teaching purposes and as a general reference for those from other fields of genetics research.

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Chromosome Mapping Cloning, Molecular Genetic Linkage Genetic Markers Journal Article Review

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C Wicking, B Williamson. 1991. From linked marker to gene.. https://doi.org/10.1016/0168-9525(91)90310-m

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