A microcomputer-based device to simulate biomechanical environments for cultured cells.

D A Wuthrich; E E Ettedgui; P R Gordon; S Gunther

doi:10.1016/0010-4825(91)90003-r

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A microcomputer-based device to simulate biomechanical environments for cultured cells.

D A Wuthrich·E E Ettedgui·P R Gordon·S Gunther

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Abstract

We describe software and hardware for a microcomputer-based cyclic strain device which applies programmed cycles of elongation and relaxation to cultured cells. This system has the potential to simulate many of the complex mechanically active environments found in living systems. As a sample application, we use it to simulate the cyclic stresses to which vascular smooth muscle cells in the arterial system are exposed.

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Arteries Biomechanical Phenomena Cells, Cultured Computer Simulation Humans Microcomputers Models, Biological Muscle, Smooth, Vascular Stress, Mechanical Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

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D A Wuthrich, E E Ettedgui, P R Gordon, S Gunther. 1991. A microcomputer-based device to simulate biomechanical environments for cultured cells.. https://doi.org/10.1016/0010-4825(91)90003-r

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