PubMed · 176613
The source did not provide an abstract. Follow the original record for more information.
Explore connections, maps & timelines
R A Limjuco, L Sherman, H D Kolodny. 1976. Isolated ACTH deficiency.. https://pubmed.ncbi.nlm.nih.gov/176613/
Cite the original work for its findings. Save a collection to share your selection of sources.
KEEP EXPLORING
The therapeutic benefit of glucocorticoids appears to derive chiefly from their suppression of immunologic and inflammatory responses, but beyond these generalized phenomena, there are a number of tissue-specific effects. Increasing knowledge of these actions is shedding light on such issues as steroid resistance and steroid-induced adrenocortical insufficiency.
Megaesophagus, hypercalcemia, and eosinophilia associated with glucocorticoid deficiency were detected in a 5-year-old neutered female Standard Poodle with concurrent hypothyroidism. Clinical and biochemical abnormalities resolved with glucocorticoid replacement treatment, and the dog was normal 29 months after diagnosis. The dog's breed and sex and the existence of a second endocrinopathy supported an underlying immunologic disorder.
Explore the source record for details and available documents.