Malignant transformation by mutant Rel proteins.

T D Gilmore

doi:10.1016/0168-9525(91)90421-l

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Malignant transformation by mutant Rel proteins.

T D Gilmore

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Abstract

A newly described family of transcriptional regulatory proteins, the Rel family, has recently been the subject of much interest. The Rel family includes proteins known to be important in Drosophila development, replication of HIV-1, oncogenesis and general transcriptional control. Nevertheless, there is still much to be learned about their precise mechanism of action, including the process by which the original member of this family, v-Rel, malignantly transforms cells.

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Amino Acid Sequence Animals Cell Transformation, Neoplastic Humans Molecular Sequence Data Mutation Oncogene Proteins v-rel Oncogenes Retroviridae Proteins, Oncogenic Transcription Factors Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.Review

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T D Gilmore. 1991. Malignant transformation by mutant Rel proteins.. https://doi.org/10.1016/0168-9525(91)90421-l

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