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PubMed · 1791878

The microcirculation and essential hypertension.

P Draaijer·J L Le Noble·K M Leunissen·H A Struyker-Boudier
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Abstract

Essential hypertension is characterized by a progressive increase of the mean arterial pressure paralleled by a concomitant increase in the total peripheral resistance. This elevated resistance is the consequence of (a) a decreased internal diameter, (b) an increased wall-to-lumen ratio or (c) a decreased number of small arteries or arterioles. A considerable part of the elevated vascular resistance is determined at the microcirculatory level. This paper reviews the studies performed to unravel the resistance-elevating mechanisms in the microvasculature of different tissues. Furthermore the possible role of the microcirculation in the pathogenesis of essential hypertension is discussed.

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P Draaijer, J L Le Noble, K M Leunissen, H A Struyker-Boudier. 1991. The microcirculation and essential hypertension.. https://pubmed.ncbi.nlm.nih.gov/1791878/

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