Advances in coronary interventional techniques.

Abstract

The practice of catheter interventional techniques for coronary artery disease is just 14 years old. Many approaches are being applied, including balloon and rotational angioplasty devices, atherectomy catheters, lasers, and stents. Considerable efforts are being made developing, marketing and comparing these technologies. Restenosis is demanding more attention amongst clinical and basic scientists. The pathophysiology of this frequent and irksome complication is still poorly understood. A number of trials are comparing strategies of PTCA against medicine and surgery. In the United States, the Bypass Angioplasty Revascularization Investigation (BARI) of PTCA versus surgery for patients with multivessel disease has nearly completed patient entry; the preliminary results are eagerly awaited. Patients in nearly all countries are benefiting from these new technologies. Their development and evaluation has been most active in North America, Europe and Japan but many of them are being clinically applied in nearly all countries. Their cost and complexity present special challenges for funding, training and evaluation.