PubMed · 183867
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Z Skrzydlewski, K Worowski. 1976. Low density lipoprotein (LDL) complexes with protamine.. https://pubmed.ncbi.nlm.nih.gov/183867/
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In the course of a follow-up of 87 subjects with known hyperlipoproteinemia a new, simplified method was tested for quantification of the individual lipoprotein fractions capable of being performed by every larger laboratory, in contrast to the expensive ultracentrifugation. The LDL/HDL ratio proved to be the conclusive parameter for daily diagnosis in hospital and general practise. This enabled the most important aspects of the lipid metabolic situation of a patient to be recognized immediately.