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PubMed · 185860

[Discriminant-analytic structure-effect relationship of qualitative biological data. Virostatic effect of isatin-beta-isothiosemicarbazones].

R Franke·W Meisske
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Abstract

"Yes/No" results from the plaque-diffusion inhibition test concerning the virostatic activity of substituted isatin-beta-isothiosemicarbazones against mengo- and vaccinia-viruses can be described discriminant analytically by means of simple substituent constants. The discriminant analysis permits quantitative structure-activity analysis of qualitative and semi-quantitative test data, thus offering a chance for theoretical synthesis optimization already at the level of rough screening.

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IndolesIsatinMengovirusStructure-Activity RelationshipThiosemicarbazonesVaccinia virusEnglish AbstractJournal Article

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R Franke, W Meisske. 1976. [Discriminant-analytic structure-effect relationship of qualitative biological data. Virostatic effect of isatin-beta-isothiosemicarbazones].. https://pubmed.ncbi.nlm.nih.gov/185860/

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