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PubMed · 186568

Accumulation of 99mTc-diphosphonate in four patients with hepatic neoplasm: case reports.

M J Guiberteau·M S Potsaid·K A McKusick
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Abstract

The accumulation of bone-seeking radiopharmaceuticals in extraosseous lesions has been reported in patients with myocardial infarctions, cerebral infarctions, and some soft-tissue tumors. While the precise mechanisms involved remain uncertain, the spectrum of abnormalities exhibiting such accumulation increases. In our laboratory, 99mTc-diphosphonate concentrated in four hepatic tumors (one cholangiocarcinoma and three metastases from colon carcinoma). This property of phosphate-related radiopharmaceuticals has not been reported previously. Awareness of the possibility of focal diphosphonate accumulation in the liver should help avoid confusion with right lower rib-cage metastasis or pleural effusion.

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AdenocarcinomaAdenoma, Bile DuctAgedCecal NeoplasmsColonic NeoplasmsDiphosphonatesFemaleHumansLiver NeoplasmsMaleMiddle AgedNeoplasm MetastasisRadionuclide ImagingTechnetiumCase ReportsJournal Article

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M J Guiberteau, M S Potsaid, K A McKusick. 1976. Accumulation of 99mTc-diphosphonate in four patients with hepatic neoplasm: case reports.. https://pubmed.ncbi.nlm.nih.gov/186568/

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