Is hsp70 the cellular thermometer?

E A Craig; C A Gross

doi:10.1016/0968-0004(91)90055-z

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Is hsp70 the cellular thermometer?

E A Craig·C A Gross

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Abstract

Cells respond to an increase in temperature by inducing the synthesis of the heat shock proteins, which are a small set of evolutionarily conserved proteins. We review the evidence leading us to suggest that the free pool of one of these proteins, hsp70, serves as a cellular thermometer that regulates the expression of all heat shock proteins.

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Animals Eukaryotic Cells Heat-Shock Proteins Prokaryotic Cells Temperature Journal Article Review

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E A Craig, C A Gross. 1991. Is hsp70 the cellular thermometer?. https://doi.org/10.1016/0968-0004(91)90055-z

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