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Cellular aging and senescence.

A McCormick·J Campisi
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Abstract

Differentiated eukaryotic cells have only a finite capacity for cell division. This limitation is thought to be a cellular manifestation of organismal aging, and a restraint to tumor progression. The molecular basis for cellular senescence is not known, but a molecular framework for understanding this phenomenon has recently been established.

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A McCormick, J Campisi. 1991. Cellular aging and senescence.. https://doi.org/10.1016/0955-0674(91)90144-n

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