Cyclic AMP and T-cell differentiation.

M A Bach; G Beaurain

PubMed · 188382

Cyclic AMP and T-cell differentiation.

Abstract

We have studied the effects of a circulating thymic factor (TF), cyclic AMP (cAMP) and prostaglandins on T-lymphocyte differentiation in the mouse using three parameters: 1) 0-bearing cell percentage evaluated by a cytotoxicity test with anti-0 serum (A0S) plus complement; 2) 0-antigen presence on rosette forming cells (RFC) assessed by the inhibition of rosette formation with A0S; 3) lymphocyte mediated cytotoxicity (LMC) against allogeneic target cells after in vivo sensitization, using a chromium release assay.

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Animals Cyclic AMP Mice Mice, Inbred Strains T-Lymphocytes Journal Article

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M A Bach, G Beaurain. Cyclic AMP and T-cell differentiation.. https://pubmed.ncbi.nlm.nih.gov/188382/

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