PubMed · 1887503
Minor histocompatibility antigens.
Abstract
Histocompatibility antigens have been studied for over 50 years because they form a major obstacle to clinical transplantation. Human minor histocompatibility antigens remain ill-defined, but minor histocompatibility loci have been mapped on nearly every mouse chromosome. Recent molecular definition of several transplantation antigens suggests that they are by-products of an immune system poised to present viral antigens, and a mutation in any gene may give rise to a new minor histocompatibility antigen.
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K F Lindahl. 1991. Minor histocompatibility antigens.. https://doi.org/10.1016/0168-9525(91)90368-z
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