Cytokines in T-cell development.

S R Carding; A C Hayday; K Bottomly

doi:10.1016/0167-5699(91)90037-t

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Cytokines in T-cell development.

S R Carding·A C Hayday·K Bottomly

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Abstract

The thymus provides a unique environment for the development of T cells, supporting both precursor cell proliferation and differentiation. The control of these processes is unknown but they may be mediated by cytokines, or other soluble factors, or by interactions with specific elements of the thymic stroma. Here, Simon Carding, Adrian Hayday and Kim Bottomly describe cellular, immunochemical and molecular studies of the production and action of cytokines within the human and mouse thymus and demonstrate their essential role in T-cell development.

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Animals Cell Communication Cell Differentiation Cytokines Humans Organ Culture Techniques T-Lymphocytes Thymus Gland Journal Article Review

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S R Carding, A C Hayday, K Bottomly. 1991. Cytokines in T-cell development.. https://doi.org/10.1016/0167-5699(91)90037-t

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