Latent infection and measles meningoencephalitis in Syrian hamsters.

Eliseeva IYa; L I Ravkina; Karmysheva VYa

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PubMed · 18920

Latent infection and measles meningoencephalitis in Syrian hamsters.

Eliseeva IYa·L I Ravkina·Karmysheva VYa

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Abstract

A strain designated 42-Edmonston was isolated from the brain of a Syrian hamster 30 days after inoculation during the neonatal period with the reference "wild" measles virus strain Edmonston which produced a latent infection accompanied by production of measles antibody and insignificant pathomorphological changes. Intracerebral inoculation with the 42-Edmonston strain of newborn, one day-and 5-7-day-old Syrian hamsters resulted in the development of acute measles encephalitis with typical clinical symptoms and pathomorphological changes. It is suggested that selection and adaptation of a neurotropic measles virus variant probably had occurred in the course of virus persistence in the Syrian hamster brain.

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Animals Animals, Newborn Antibodies, Viral Antigens, Viral Brain Cricetinae Disease Models, Animal Measles virus Meningoencephalitis Mesocricetus Journal Article

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Eliseeva IYa, L I Ravkina, Karmysheva VYa. 1977. Latent infection and measles meningoencephalitis in Syrian hamsters.. https://pubmed.ncbi.nlm.nih.gov/18920/

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