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PubMed · 1906199

Selenium in rheumatic diseases.

A M Peretz·J D Nève·J P Famaey
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Abstract

Selenium is involved in several important biochemical pathways relevant to rheumatic diseases. Experimental and clinical studies suggest that selenium modulates the inflammatory and immune responses. Patients suffering from inflammatory rheumatic diseases often have low selenium levels, but this finding does not correlate with disease severity. Selenium supplementation needs stricter selection criteria and better ascertainment of dose to obtain a stimulatory or inhibitory effect relevant to the disease state. Prevention of marginal selenium deficiency by moderate supplementation might enhance host defense mechanisms.

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AnimalsAntibody FormationArachidonic AcidArachidonic AcidsArthritis, RheumatoidFree RadicalsHumansInflammationOxygenPhagocytesRheumatic DiseasesSeleniumJournal ArticleResearch Support, Non-U.S. Gov'tReview

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BibTeXRIS

A M Peretz, J D Nève, J P Famaey. 1991. Selenium in rheumatic diseases.. https://doi.org/10.1016/0049-0172(91)90031-t

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