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A disintegration test for vaginal tablets: comparison with BP test.

M Yamaguchi·K Tanno·K Sugibayashi·Y Morimoto
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Abstract

To improve the disintegration test for vaginal tablets described in the British Pharmacopoeia (BP), a monitoring apparatus was added, and tested with seven effervescent and five non-effervescent tablets. A tablet was placed on the metal disc of the BP disintegration apparatus, and the guided plate was placed on the tablet. The guided plate moved downward smoothly in a cylinder as the tablet disintegrated. The movement was recorded by using a kymograph. The end-point and process of disintegration of the tablet were automatically recorded and the results obtained suggest that the modified test is a useful tool for the quality control of vaginal tablets.

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FemaleHumansPharmacopoeias as TopicTabletsTechnology, PharmaceuticalUnited KingdomVaginaComparative StudyJournal Article

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M Yamaguchi, K Tanno, K Sugibayashi, Y Morimoto. 1990. A disintegration test for vaginal tablets: comparison with BP test.. https://doi.org/10.1111/j.2042-7158.1990.tb07023.x

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