PubMed · 1993560
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R M Fine. 1991. Acanthosis nigricans.. https://doi.org/10.1111/j.1365-4362.1991.tb05872.x
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Acanthosis nigricans in children is usually associated with obesity. Generalized acanthosis nigricans in childhood is rare. We report a 13-year-old boy with an 8-year history of generalized hyperpigmentation and velvety thickening of the skin. Despite an extensive physical and laboratory examination no evidence of underlying endocrinological or neoplastic disease was found.
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