Pancreatic acinar cell metabolism and function.

P D Webster; O Black; D L Mainz; M Singh

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PubMed · 199525

Pancreatic acinar cell metabolism and function.

P D Webster·O Black·D L Mainz·M Singh

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Abstract

This review outlines progress made during the past 11 years in research related to pancreatic acinar cell metabolism and function. We have reviewed information gained at the cellular level concerning structural and functional relationships, and effects of fasting and feeding, as well as the action of gastrointestinal hormones and cholinergic agonists on acinar cells. In toto, this information outlines a significant role for gastrointestinal hormones as mediators of secretion, synthesis, and control of trophism. This information provides a basis for more sophisticated inquiries as to the mechanisms of injury of alcohol and drugs. The information may prove helpful in developing diagnostic modalities for pancreatic disease, as well as understanding the processes involved in neoplastic transformation.

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Amino Acids Animals Calcium Digestion Energy Metabolism Fasting Humans Hypertrophy Nucleotides, Cyclic Pancreas Pancreatic Juice Phospholipids Receptors, Cell Surface Receptors, Cholinergic Regeneration Stimulation, Chemical Journal Article Research Support, U.S. Gov't, Non-P.H.S.Research Support, U.S. Gov't, P.H.S.

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P D Webster, O Black, D L Mainz, M Singh. 1977. Pancreatic acinar cell metabolism and function.. https://pubmed.ncbi.nlm.nih.gov/199525/

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