PubMed · 2016891
A probabilistic view on steady-state enzyme reactions.
Abstract
A new theoretical description of steady-state enzyme reactions is proposed. The description is based on the concepts of the probability theory instead of the conventional formalism of chemical kinetics. A general steady-state rate equation is obtained using a probabilistic model of the catalytic act. As a result, the classical problems of enzyme kinetics can be formulated and considered in a different aspect. It is shown that the new theory presents a clearer treatment of some commonly obscure questions, such as the steady-state establishment. The theory also gives additional possibilities in the interpretation of the experimental results of traditional methods and proposes certain new ways in experimental investigations of enzymes.
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A K Mazur. 1991-01-21. A probabilistic view on steady-state enzyme reactions.. https://doi.org/10.1016/s0022-5193(05)80342-x
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