XLMR genes: update 1990.

G Neri; F Gurrieri; A Gal; H A Lubs

doi:10.1002/ajmg.1320380204

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PubMed · 2018056

XLMR genes: update 1990.

G Neri·F Gurrieri·A Gal·H A Lubs

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Abstract

We have identified 39 X-linked conditions in which mental retardation seems to be the primary characteristic, although pathogenesis is unknown. These conditions can be subdivided into syndromal and non-syndromal, depending on the existence of a recognizable pattern of minor anomalies and/or malformations, or lack thereof. Seventeen genes have been regionally mapped onto the X chromosome. However, in 14 instances the data were derived from a single family and most lod scores were less than 3.0.

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Chromosome Mapping Congenital Abnormalities Female Genetic Markers Humans Intellectual Disability Male X Chromosome Journal Article Research Support, Non-U.S. Gov't

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G Neri, F Gurrieri, A Gal, H A Lubs. XLMR genes: update 1990.. https://doi.org/10.1002/ajmg.1320380204

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