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PubMed · 201853

Recent excitement in the DNA replication problem.

B Alberts·R Sternglanz
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Abstract

It is now possible to reproduce most of the reactions involved in DNA replication using prokaryotic enzymes in vitro. Such systems have revealed that DNA replication is a complex process depending on a relatively large number of proteins, and that nucleoside triphosphate hydrolysis energy is used at several discrete steps. Much of the complexity of DNA replication may arise from the need for extreme copying fidelity.

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Adenosine TriphosphateColiphagesDNA HelicasesDNA ReplicationDNA, BacterialDNA, ViralDNA-Directed DNA PolymeraseEscherichia coliMutationNucleic Acid ConformationJournal ArticleResearch Support, U.S. Gov't, P.H.S.Review

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B Alberts, R Sternglanz. 1977-10-20. Recent excitement in the DNA replication problem.. https://doi.org/10.1038/269655a0

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