Cell culture model systems to study HDV expression, replication and pathogenesis.

E J Gowans; T B Macnaughton; A R Jilbert; C J Burrell

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PubMed · 2020706

Cell culture model systems to study HDV expression, replication and pathogenesis.

E J Gowans·T B Macnaughton·A R Jilbert·C J Burrell

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Abstract

Due to the transient nature of HDV replication in natural and experimental hosts and to the inability of the virus to replicate in easily handled cell lines, studies of the replication and expression of HDV have been impeded. These difficulties have been overcome by the development of the cell lines described in this paper.

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Animals Antigens, Viral Blotting, Northern Cell Line Cloning, Molecular Gene Expression Regulation, Viral Hepatitis D Hepatitis Delta Virus Hepatitis delta Antigens Humans Liver Pan troglodytes RNA, Viral Radioimmunoassay Recombinant Proteins Transcription, Genetic Virus Replication Journal Article Research Support, Non-U.S. Gov't

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E J Gowans, T B Macnaughton, A R Jilbert, C J Burrell. 1991. Cell culture model systems to study HDV expression, replication and pathogenesis.. https://pubmed.ncbi.nlm.nih.gov/2020706/

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