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PubMed · 2054116

Leprosy and cell-mediated immunity.

G Kaplan·Z A Cohn
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Abstract

The intradermal injection of the purified protein derivative of tuberculin into lepromatous leprosy patients leads to a local cell-mediated immune response and to the extensive destruction of Mycobacterium leprae. This local response also occurs after intradermal injection of recombinant human interleukin-2; when administered over an 8-day period interleukin-2 evokes a systemic cell-mediated immune response and a reduction in the bacillary burden.

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AnimalsCytokinesHumansImmunity, CellularKiller Cells, NaturalLeprosyLymphocyte ActivationLymphokinesMicePhagocytesT-LymphocytesJournal ArticleResearch Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, P.H.S.Review

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BibTeXRIS

G Kaplan, Z A Cohn. 1991. Leprosy and cell-mediated immunity.. https://doi.org/10.1016/0952-7915(91)90083-d

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