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Nicotine exerts differential effects on different CA1 hippocampal cell types.

L J Reece·P A Schwartzkroin
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Abstract

The effects of (-) nicotine hydrogen tartrate (NHT) were examined on several cell types in the CA1 region of rat hippocampus. The results indicate that nicotine may have a preferential net inhibitory effect on basket cells and an excitatory effect on oriens/alveus interneurons. The resultant effects of nicotine on pyramidal cells may thus be a product of complex local circuit interactions.

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AnimalsDendritesHippocampusIn Vitro TechniquesInterneuronsMembrane PotentialsNicotinePyramidal TractsRatsComparative StudyJournal ArticleResearch Support, U.S. Gov't, P.H.S.

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L J Reece, P A Schwartzkroin. 1991-02-01. Nicotine exerts differential effects on different CA1 hippocampal cell types.. https://doi.org/10.1016/0006-8993(91)90520-6

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