Transgenic mice as immune system models.

G Morahan

doi:10.1016/0952-7915(91)90054-5

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Transgenic mice as immune system models.

G Morahan

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Abstract

In the past year, transgenic mice have continued to be powerful models for the investigation of various features of the immune system, particularly for studies of lymphocyte differentiation and tolerance. Major achievements have included the definition of intra-thymic selection events in T-cell differentiation, and the demonstration of extra-thymic tolerance resulting from clonal energy.

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Animals Autoimmune Diseases Forecasting Immune System Immune Tolerance Mice Mice, Transgenic Models, Biological Receptors, Antigen, B-Cell Receptors, Antigen, T-Cell Journal Article Research Support, Non-U.S. Gov't Review

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G Morahan. 1991. Transgenic mice as immune system models.. https://doi.org/10.1016/0952-7915(91)90054-5

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